Pyroptosis Takes Aim at Neurodevelopment

The Human Life Bill: personhood revisited, or Congress takes aim at Roe v. Wade.

Taking aim at targets.

population: the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) population study. Int J Epidemiol 2004; 33: 189–198 23. Yuyun MF, Khaw KT, Luben R et al. Microalbuminuria and stroke in a British population: the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) population study. J Intern Med 2004; 255: 247–256 24. Harwell TS, Nelson RG, Little RR e...

Pyroptosis

Injury and physical trauma may inflict accidental cell death, but we have come to realize during the past four decades that cells may also actively engage cell death when needed. These regulated cell death forms are intrinsically connected with human embryonic development, homeostatic maintenance and disease pathology. For instance, the human body is composed of approximately 10(14) cells, mill...

Taking aim at cholera

In 1854, John Snow’s work on cholera in London immortalised the power of mapping as a tool for disease prevention and control. Over 160 years later, a more ambitious effort to map cholera has been reported in The Lancet. Forgoing so-called shoe leather epidemiology in favour of big data, Justin Lessler and colleagues used 279 cholera datasets covering 2283 locations in 37 countries, and cluster...

Taking aim at Sox18

A small molecule called Sm4 can disrupt interactions involving a transcription factor called Sox18, while having little impact on other members of the SoxF family.